Quantitative mass spectrometry methods for pharmaceutical analysis
نویسندگان
چکیده
منابع مشابه
Qualitative and quantitative analysis of pharmaceutical compounds by MALDI-TOF mass spectrometry.
In this report, we discuss key issues for the successful application of MALDI-TOF mass spectrometry to quantify drugs. These include choice and preparation of matrix, nature of cationization agent, automation, and data analysis procedures. The high molecular weight matrix meso-tetrakis(pentafluorophenyl)porphyrin eliminates chemical noise in the low-mass range, a "brushing" spotting technique i...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
سال: 2016
ISSN: 1364-503X,1471-2962
DOI: 10.1098/rsta.2015.0366